Esters are such a ubiquitous and important functional group, and they're often one of the first to be encountered in preparative chemistry labs, since they are so readily formed. Hot on the heels of his recent Acetals and Ketals Functional Group Spotlight, MedChemProf has returned to the world of carboxylic acid derivatives with this overview of Esters. Once again - be sure to try out the interactive 3D models! - Mark
The good-old-fashioned chemistry set. I've loved science, and chemistry in particular, since I was a little boy, and some of my fondest memories are of experimenting with my chemistry set. And now, as a father of three curious little scientists, I've searched for something similar! So, how does the new breed of chemistry set on offer from MEL Science stack up to my cherished memories?..
Acetals and Ketals have a special place in my OChem-loving heart! Not least because I spent most of my PhD trying to make spiroacetal structures that were part of a natural product called spongistatin. In fact, I like them so much that my last major research project before leaving academia was about trying to synthesize spiroacetals via a new synthetic route. More about that another day! Today, we have another Functional Group Spotlight by MedChemProf, after the popularity of his Amide Functional Group Spotlight. Read on and be sure to have a play with the cool interactive molecules scattered throughout the post! - Mark
I'm SO excited by today's post! I've brought onboard McKenna, who runs the gorgeous and hugely popular instagram account @magnolia_med, documenting her pre-med study journey. McKenna shares her secrets for how to study organic chemistry - how she turned a 65 into an A in Organic Chemistry, and her top tips for the ACS final exam!
Amides are one of the most important functional groups in Organic Chemistry. They're ubiquitous in biology and medicine and understanding their structure and properties is vital to understanding what gives proteins their shapes. Here with a special guest Spotlight on Amides is MedChemProf, an Associate Professor in a School of Pharmacy, with strong interest in modern technology in teaching. Read on and be sure to have a play with the cool interactive molecules scattered throughout the post! - Mark
Once you've mastered the art of drawing chair conformations, it's time to stick some axial and equatorial substituents on those beautiful chairs. In marking thousands of exam papers, there's 2 mistakes that I've seen over and over again. Here's how to avoid those mistakes ace any chair conformations in your OChem exams.
Let's face it, chair cyclohexanes are not a shape that comes naturally for anyone to draw. That's why you need a system to get them right. Here is how to draw chair conformations in 39 seconds...
Chiral centers come in two flavours - vanilla or chocolate chip... Just kidding! They come in R and S varieties. There's a three-step process for assigning the R or S, and one of the steps in putting the lowest priority group at the back, away from you. But what do you do when the lowest priority group isn't behaving and isn't already at the back? Read on and watch the video to find out two simple strategies that will rock your chiral world!
If there's one thing you're guaranteed in Organic Chemistry exams, it's to be asked mechanism questions! Reaction mechanisms in organic chemistry are the bread and butter of exam questions! So how do you avoid the most common mistakes?